Glossary
Adherence: Taking your medications regularly as prescribed by an HCP.
AIDS: Acquired Immune Deficiency Syndrome.
AIDS-defining infection or condition: Also known as opportunistic infections or conditions. These are usually illnesses that a person not infected with HIV normally wouldn’t get.
Antiretroviral drugs: Also referred to as ARVs. Antiretroviral drugs help to manage and control the virus by slowing down HIV’s ability to replicate.
APTIVUS/r: Combination of APTIVUS® (tipranavir) capsules taken with Norvir® (ritonavir).
CD4+ cells: Also known as T cells, CD4+ cells are part of your immune system. They identify and fight infections and other diseases that invade your body.
Chronic hepatitis B infection: A serious disease of the liver caused by the hepatitis B virus (HBV). It is mostly transmitted through contact with blood and other bodily fluids, including sexual contact.
Chronic hepatitis C infection: A serious disease of the liver caused by the hepatitis C virus (HCV). It mostly affects people who share needles, have been on dialysis, have liver disease, or go through frequent blood transfusions or sexual contact.
Combination therapy: APTIVUS/r must be used with at least 2 other anti-HIV medicines. This is referred to as combination therapy.
Genotypic test: A test to see if the HIV virus has developed mutations that may be resistant to certain medications.
HAART: Highly Active Anti-Retroviral Therapy. Three or four anti-HIV drugs with different methods of working are taken together to avoid resistance.
HCP: An HCP, or healthcare provider, is the doctor, nurse, pharmacist, or other healthcare professional that is responsible for your HIV care.
Hemophilia: An inherited disease that prevents the blood from clotting properly.
HIV: Human Immunodeficiency Virus. HIV infects healthy immune cells and prevents them from protecting the body from infection and disease.
Immune system: Defends your body from infection and disease. HIV and AIDS can harm the functioning of your immune system.
Lipid: Another word for cholesterol and/or triglycerides.
Phenotypic test: A test to see if a drug is effective against your virus by measuring the amount of a specific drug needed to keep the HIV virus from reproducing.
Protease inhibitor: A class of anti-HIV drugs that work by blocking protease, an enzyme in a virus that helps it make copies of itself.
Regimen: When used in the context of treatment, a regimen is a combination of medications taken together. It can also be called a “cocktail.”
Replicate: When used in the context of HIV, replicate is the word used to describe the action that HIV cells undergo when they make new copies of themselves.
Resistance: A change in the virus that makes HIV medications work less well.
Undetectable: Reducing the amount of HIV in your blood to a level so low that routine testing cannot detect it—a goal of anti-HIV treatment.
Viral load: The amount of HIV in a sample of blood.
Please consult the Full Prescribing Information as well as the Patient Package Insert (PPI) including boxed WARNINGS, and Important Safety Information for APTIVUS.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.


