How to Take APTIVUS

Take APTIVUS exactly as your healthcare provider (HCP) has prescribed. You should check with your HCP or pharmacist if you are not sure. You must take APTIVUS at the same time as Norvir® (ritonavir). This is known as APTIVUS/r. The adult dose is 500 mg (two 250 mg capsules or 5 mL of oral solution) of APTIVUS, together with 200 mg (two 100 mg capsules or 2.5 mL of oral solution) of ritonavir, twice per day. APTIVUS/r must be used with other anti-HIV medicines.

Children 2 years of age or older can also take APTIVUS with ritonavir. The child’s healthcare professional will decide the right dose based on the child’s weight or size. The dose should not exceed the recommended adult dose.

APTIVUS Capsules or Oral Solution + ritonavir

• Do not change your dose or stop taking APTIVUS without talking to your HCP
• If you take too much APTIVUS, call your HCP or poison control center right away
• If you forget to take APTIVUS, take the next dose of APTIVUS, together with Norvir as soon as possible. Do not take a double dose to make up for the missed dose
• It is very important to take all your anti-HIV medicines as prescribed and at the right times of day. This can help your medicines work better. It also lowers the chance that your medicines will stop working to fight HIV (drug resistance)
• When your APTIVUS supply starts to run low, get more from your HCP or pharmacy. This is very important because the amount of virus in your blood may increase if the medicine is stopped for even a short period of time. The HIV virus may develop resistance to APTIVUS and become harder to treat. You should NEVER stop taking APTIVUS or your other HIV medicines without talking with your HCP